More studies on outcomes using biochemical diagnostic tests are needed: findings from the Danish Society of Clinical Biochemistry.

by spectrophotometer, readings for all samples were higher than those for the 0 ng/L calibrator; OOM extracts provided signals that were well above those of the 400 ng/L calibrator. In summary, simple aqueous extracts from small portions of 6 different OOM-associated tumors revealed very high FGF-23 concentrations as assessed by the calibrator assay; FGF-23 concentrations were also readily detectable by a modified rapid test that takes 30 min to complete. Like intraoperative parathyroid hormone assays (5 ), this rapid assay could be performed in or near the operating room, especially because visual inspection of the test plate was sufficient to detect FGF-23 in all 6 tumors tested. The assay may furthermore help define, intraoperatively, the disease-free margins of tumors located in areas that are difficult to access surgically.